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Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome

Md Ralib, Azrina and Mat Nor, Mohd Basri (2015) Acute kidney injury in a Malaysian intensive care unit: assessment of incidence, risk factors and outcome. Journal of Critical Care, 30 (3). pp. 636-642. ISSN 0883-9441

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Purpose Acute Kidney Injury (AKI) is common and carries a high mortality rate. Most epidemiological studies were retrospective and were done in Western populations. We aim to assess its incidence utilising both urine output and creatinine criteria, and its association with risk factors and outcome. Material and Methods This was a single centre, prospective observational study. All ICU patients more than 18 years were screened for inclusion in the study. Admission of less than 48 hours, post-elective surgery and ICU readmission were excluded. Results A total of 143 patients were recruited, of these, 65% had AKI, of which 18 (19%) were Stage 1, 23 (25%) Stage 2 and 52 (56%) Stage 3. Independent risk factors for AKI includes high APACHE II score and septic shock (OR of 1.20 (1.09 to 1.33) and 8.41 (1.49 to 47.6), respectively). 38% were classified as AKICr, and 61% as AKIuo, and in 34%, both AKICr and AKIuo were present. AKI was an independent risk factor for mortality (HR 2.61 (1.06 to 6.42)). Conclusions AKI is common in our ICU, and almost half are highest severity stage. Patients with high severity of illness and septic shock were at risk for AKI. The presence of AKI independently predicted mortality.

Item Type: Article (Journal)
Additional Information: 3934/41224.
Uncontrolled Keywords: Acute kidney injury, intensive care unit, epidemiology, risk factors, dialysis mortality
Subjects: R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Anaesthesiology & Intensive Care
Depositing User: Prof Azrina Md Ralib
Date Deposited: 08 Jun 2015 13:31
Last Modified: 06 Apr 2017 16:14
URI: http://irep.iium.edu.my/id/eprint/41224

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