Md Aris, Mohd Aznan and Khattak, Muhammad Muzaffar Ali Khan and Abdullah, Nor Zamzila and Mohd Rus, Razman and Draman, Samsul (2014) Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents. American Journal of Clinical Medicine Research, 2 (6). pp. 106-110. ISSN 2328-4005 (P), 2328-403X (o)
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Abstract
Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabolic syndrome (based on the criteria of the International Diabetes Federation (IDF) world-wide definition) and another 76 matching healthy respondents. The factors which were studied for possible differences and association include central obesity (body mass index (BMI) & waist circumference (WC), hypertension (systolic blood pressure (SBP), diastolic blood pressure (DBP), dyslipidemia (total cholesterol (Tc), high density lipoprotein Cholesterol (HDL-c), low density lipoprotein Cholesterol (LDL-c), Triglyceride (TG) and Adiponectin (AD), fasting plasma glucose and history of smoking. The data collected was statistically analyzed using SPSS statistical software version 12.0. Two tests were performed including paired t-test and Pearson correlation analysis. The collected data revealed some interesting differences for the healthy and metabolic syndrome respondents. There were significant (P<0.01) differences for central obesity and hypertension. There were also significant (P<0.01, P<0.1, P<0.01) differences for TG, HDL and fasting plasma glucose. More importantly, AD concentration was significantly (P<0.05) higher in normal healthy respondents. The AD showed strong negative association (r = - 2.91, P<0.001) with FBG and positive association (r = 2.89, P<0.001) with HDL-c. The present study provides baseline information on the predication of metabolic syndrome in Malaysian population.
Item Type: | Article (Journal) |
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Additional Information: | 4632/40261 |
Uncontrolled Keywords: | adiponectin, abdominal obesity, metabolic syndrome, hypertension, dyslipidemia |
Subjects: | R Medicine > R Medicine (General) |
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) |
Depositing User: | Prof Dr Mohd Aznan Md Aris |
Date Deposited: | 27 Dec 2014 21:23 |
Last Modified: | 25 Feb 2016 11:07 |
URI: | http://irep.iium.edu.my/id/eprint/40261 |
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