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Conversion of strontium hydroxyapatite nanopowders to porous scaffolds for bone implant application

Sopyan, Iis and C. M., Mardziah and Koay Mei, Hyie and N. R., Nik Roselina (2014) Conversion of strontium hydroxyapatite nanopowders to porous scaffolds for bone implant application. Applied Mechanics and Materials, 607. pp. 3-6. ISSN 1660-9336

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Abstract

The fabrication of strontium hydroxyapatite (SrHA) porous scaffolds was accomplished by using polymeric sponge method. To prepare the porous samples, the synthesized SrHA nanopowders were mixed with distilled water and appropriate amount of dispersing agent followed by drying in the ambient air and sintering at 1300°C. The compressive strength of the materials was strongly influenced by the porosity, while there was almost no dependence on the crystallinity of the powders since XRD patterns showed high crystallinity of HA phase for all porous samples. Morphological evaluation by FESEM revealed that the SrHA scaffolds were characterized by macro-micro interconnected porosity, which replicates the morphology of the cancellous bone. Compression test on the porous scaffolds demonstrated that doping 10 mol% of strontium in HA has increased the compressive strength by a factor of two compared to the undoped HA with 1.81±0.26 MPa at 41% porosity.

Item Type: Article (Journal)
Additional Information: 4809/38166
Uncontrolled Keywords: Compressive strength; Nanopowders; Porous scaffolds; Strontium hydroxyapatite
Subjects: T Technology > TA Engineering (General). Civil engineering (General) > TA164 Bioengineering
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Engineering > Department of Manufacturing and Materials Engineering
Depositing User: PROF. DR. IIS SOPYAN
Date Deposited: 10 Sep 2014 09:14
Last Modified: 19 Jun 2018 14:58
URI: http://irep.iium.edu.my/id/eprint/38166

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