Chronic khat consumption and its effect on ovarian structure in mice and their offspring

AlBadri, Cinaria and Al-Ani, Imad Matloub Dally and Hiba, Hassan (2014) Chronic khat consumption and its effect on ovarian structure in mice and their offspring. Annals of Microscopy, 14. pp. 64-69. ISSN 0219-2209

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Abstract

Khat is considered a psychoactive drug and has many side effects on different parts of the body organs. In this study the effects of khat on ovarian structure in parental mice and their offspring were investigated. Twelve male and twelve female mice were given orally a dose of 50mg/kg body weight of khat extract by gastric gavage for 4 and 8 weeks. After four weeks of treatment, the male and female mice were allowed to mate. Khat treatment continued for the male mice and for the female mice during pregnancy and after giving birth to their offsprings up to 8 weeks. Adult offspring and their parent were killed at the 4th and 8th weeks of treatment. Histological examination of the ovaries showed many corpus luteum and developing Graafi an follicles with mononuclear infi ltration.

Item Type:	Article (Journal)
Additional Information:	5849/36823
Uncontrolled Keywords:	Ovaries, khat, offspring, corpus luteum
Subjects:	Q Science > QL Zoology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Basic Medical
Depositing User:	Assoc. Prof Dr.. Imad Matloub Dally Al-Ani
Date Deposited:	06 Jun 2014 09:28
Last Modified:	20 Jun 2018 09:33
URI:	http://irep.iium.edu.my/id/eprint/36823

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