In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff

Khan, Farman Ullah and Md. Jaffri, Juliana and Bakhtiar, M. Taher (2013) In-vitro antifungal and antibacterial activities of rhizomes extracts of Alpinia galanga and Alpinia conchigera griff. In: International Conference on Natural Products 2014, 18th-19th March 2014, Palm Garden Hotel, IOI Resorts, Putrajaya, Malaysia.

PDF - Published Version Restricted to Repository staff only Download (2MB) | Request a copy

Abstract

Alpinia galanga and Alpinia conchigera are belongs to the Zingiberaceae family, distributed in Asia and particularly in the Southeast Asia. The rhizomes of A. galanga have been extensively used as condiment for flavoring and local medicines for the stomach ache, carminative and treating diarrhea. In traditional medicine A. conchigera has been used to treat illnesses such as muscle pain and to stop bleeding. The aims of this study to evaluate the antifungal and antibacterial activities of A. galanga and A. canchigera on several strains of microbes including those which are associated with skin infection. To determine the antibacterial and antifungal activities of A. galanga and A. conchigera, disc diffusion method was used. The antibacterial and antifungal activities of hexane, dichloromethane and methanolic extracts of A. galanga and A. conchigera have been evaluated against gram positive and gram negative bacteria including multi-drug resistant Staphylococcus aureus (MRSA) and fungi such as Trichophyton rubrum, Microsporum canis and Candida albicans, using daptomycin, streptomycin and nystatin as standards respectively. The hexane and methanol extracts showed significant antibacterial and antifungal activities with the zone of inhibition ranging from 14-26 mm, while MRSA was the most susceptible to the hexane extract of A. conchigera. The MIC of both plant A. galanga and A. conchigera were found 35.61 and 30.5 ug/mL respectively against MRSA.

Item Type:	Conference or Workshop Item (Speech/Talk)
Additional Information:	4162/36158
Uncontrolled Keywords:	Alpinia galanga, Alpinia conchigera griff,
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User:	Dr Muhammad Taher
Date Deposited:	02 Apr 2014 11:18
Last Modified:	16 Apr 2014 08:50
URI:	http://irep.iium.edu.my/id/eprint/36158

Actions (login required)

View Item