Antioxidant activity of different extracts from leaves of Pereskia bleo (Cactaceae)

Hassanbaglou, Behnaz and Abdul Hamid, Azizah and A. M., Roheeyati and Mohd Saleh, Norihan and Abdulamir, AhmadSahib and Khatib, Alfi and Sabu, MC (2012) Antioxidant activity of different extracts from leaves of Pereskia bleo (Cactaceae). Journal of Medicinal Plants Research, 6 (15). pp. 2932-2937. ISSN 1996-0875

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Abstract

The present study was conducted to assess the antioxidant properties of ethanol, ethyl acetate, methanol and hexane extracts from leaves of Pereskia bleo using 2,2-diphenyl-1-picrylhydrazyl method (DPPH assay), ferric reducing antioxidant power (FRAP assay) and β-Carotene-Linoleic acid methods. Total phenolic compounds (TPC) and flavonoids of the leaves of P. bleo were measured using Folin-Ciocalteu and HPLC methods respectively. Results of the present study showed that Ethyl acetate extract of P. bleo leaf exhibited significantly (p < 0.05) higher antioxidant activity as measured using DPPH free radical (IC50), FRAP and β-carotene-linoleic assays than that of hexane extract, methanol extract and ethanol extract. Pereskia bleo leaf was also found to contain high amounts of bioactive compounds including total phenolic compounds (109.43 ±0.84 mg GAE/g), epicatechin (575± 0.04 mg/100g), quercetin (110.94 ±0.12 mg/100g), catechin (918 ± 0.01 mg/100 g) and myricetin (9.49±0.55 mg/100g) while the concentrations of α- tocopherol, β-carotene and lycopene were found to be higher (69±0.25, 51.97±1.18 mg/100 g, 92.46±0.41 μg/g), respectively.

Item Type:	Article (Journal)
Additional Information:	6915/33294 ISI/SCOPUS
Uncontrolled Keywords:	Pereskia bleo, antioxidant activity, total phenolic compounds, total flavonoid compounds
Subjects:	Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User:	Dr. Alfi Khatib
Date Deposited:	13 Dec 2013 15:51
Last Modified:	13 Dec 2013 16:34
URI:	http://irep.iium.edu.my/id/eprint/33294

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