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A review on the formulation and analysis of anti-diabetic agent: Gliclazide

Helaluddin , Abul Bashar Mohammed and Alaama, Mohammed and Abdualkader, Abdualrahman Mohammed and Awang, Mohamed and Ahmed, Qamar Uddin and Abbas, Syed Atif (2013) A review on the formulation and analysis of anti-diabetic agent: Gliclazide. Advanced Materials Research, 810. pp. 159-172. ISSN 1022-6680

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Abstract

Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to have many other important effects, such as: suppression of platelet functions, antithrombotic actions, decreased the production of tumour necrosis factor (TNF) á by endothelial cells and other effects. The unique activities of gliclazide has open a new avenue for the drug development research. This work is aimed to provide comprehensive information about gliclazide and its current research activities.

Item Type: Article (Journal)
Additional Information: 4478/32319
Uncontrolled Keywords: Gliclazide, formulation, analysis, antidiuretic, sulfonylurea
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User: Dr. A. B. M. Helal Uddin
Date Deposited: 17 Oct 2013 12:26
Last Modified: 15 Dec 2013 08:16
URI: http://irep.iium.edu.my/id/eprint/32319

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