Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum

Nissad, Attoumani and Darnis, Deny Susanti and Bakhtiar, M. Taher (2013) Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum. Journal of Coastal Life Medicine, 3 (2). pp. 1-5. ISSN 2309-6152 (O), 2309-5288 (P)

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Abstract

Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the antimicrobial activity was determined by disc diffusion method. Results: All the tested extracts showed antioxidant and antimicrobial properties. The extracts showed moderate antimicrobial activity against S. aureus with zone of inhibition values of 10, 11 and 12 mm for n-hexane, DCM and methanol extracts respectively at 30 µg/disc. n-Hexane showed low antimicrobial activity against P. aeruginosa (5 mm) at 30 µg/disc. The total phenolic test showed that methanol has high phenolic content (162.25 mg GAE/g of extract) compared to the other extracts. Conclusion: The ability of the extracts to inhibit microbial growth at a concentration of 30 µg/disc indicated the its potent antimicrobial activity.

Item Type:	Article (Journal)
Additional Information:	5641/32204
Uncontrolled Keywords:	Calophyllum symingtonianum , A n t i o x i d a n t , A n t i m i c r o b i a l , T o t a l p h e n o l i c c o n t e n t
Subjects:	R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User:	Dr Muhammad Taher
Date Deposited:	03 Oct 2013 15:48
Last Modified:	12 Jun 2018 08:31
URI:	http://irep.iium.edu.my/id/eprint/32204

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