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The mechanisms of neuropathic pain: an overview for psychiatrists

Pridmore, Saxby A. and Pasha, Iqbal and Kahn, Umeed (2002) The mechanisms of neuropathic pain: an overview for psychiatrists. German Journal of Psychiatry, 5 (1). pp. 35-39. ISSN 1433-1055

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Abstract

To present an overview of the mechanisms of neuropathic pain. Method: An extensive review of the scientific literature. Results: Neuroplastic changes are described under the headings of: ectopic discharge, sensitizationof sensory terminals, cross-excitation, neurotransmitter change, coupling between the sympathetic and sensory nervous systems, spinal cord reorganization, spinal cord increased excitability, spinal cord decreased inhibition,supraspinal influences. Conclusions: These mechanisms increase our understanding of the patient with neuropathic pain and open the door for therapeutic advances in this field. They also extend our understanding of the nature of the nervous system more generally, and may provide pathophysiologic models of psychiatric disorders

Item Type: Article (Journal)
Additional Information: 2824/31476
Uncontrolled Keywords: neuropathic pain, psychiatry, models of psychopathology
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology > RM695 Physical medicine. Physical therapy
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Medicine > Department of Psychiatry
Depositing User: Assoc. Prof. Umeed Ali Khan
Date Deposited: 23 Sep 2013 15:08
Last Modified: 23 Sep 2013 15:08
URI: http://irep.iium.edu.my/id/eprint/31476

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