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A case-control study of influenza vaccine effectiveness among Malaysian pilgrims attending the Haj in Saudi Arabia

Mustafa, Amal Nasir and Abdullah, Nasuruddi and Bradford D, Gessner and Raman, Ismail and Yusoff, Ahmad Faudzi and Ishak, Ilina and Mohd Ismail , Merican (2003) A case-control study of influenza vaccine effectiveness among Malaysian pilgrims attending the Haj in Saudi Arabia. International Journal of Infectious Diseases, 7 (3). pp. 210-214. ISSN 1201-9712

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Abstract

Objectives: To determine influenza vaccine effectiveness against clinically defined influenza-like illness among Malaysian pilgrims attending the Haj in Saudi Arabia. Methods: During February and March 2000, the authors conducted an unmatched case-control study. Case patients were identified at one of five hotel clinics, while controls were residents of these hotels who had not attended a clinic. Results: Among 820 case patients–84% of whom had received antibiotics—and 600 controls, the adjusted vaccine effectiveness against clinic visits for influenza-like illness was 77% (95% confidence interval: 69,83), and that against receipt of antibiotics was 66% (95% confidence interval, 54, 75). The vaccine did not prevent clinic visits for non-influenza-like upper respiratory tract illness (adjusted vaccine effectiveness, 20%; 95% confidence interval: −24,49). Conclusions: Influenza vaccine was effective in preventing clinic visits for influenza-like illness and antibiotic use. Pilgrims traveling to the Haj in Saudi Arabia should consider influenza vaccination use.

Item Type: Article (Journal)
Additional Information: 3482/30760
Uncontrolled Keywords: Influenza A virus; Influenza B virus; Influenza Vaccines,
Subjects: R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Medicine > Department of Surgery
Depositing User: Prof. Dr. Nasuruddin Hj. Abdullah
Date Deposited: 13 Aug 2013 07:27
Last Modified: 13 Aug 2013 07:27
URI: http://irep.iium.edu.my/id/eprint/30760

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