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Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience

Sharifudin, Mohd Ariff and Wan, Zulmi and Wan Ismail, Wan Faisham Numan and Mat Zin, Nor Azman and Mohamed Amir, Nawaz Hussain (2013) Outcome of surgical treatment of pelvic osteosarcoma : Hospital Universiti Sains Malaysia experience. Malaysian Orthopaedic Journal, 7 (1). pp. 56-62. ISSN 1985-2533

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We reviewed the surgical treatment and outcomes of 13 patients with pelvic osteosarcoma treated in our centre in the past decade. The study sample included 9 males and 4 females with a mean age of 28.1 years. Four patients had ileal lesions, five had acetabulum lesions, one had a ischiopubis lesion, and three had involvement of the whole hemipelvis. Seven patients presented with distant metastases at diagnosis. Limb salvage was performed in 6 patients and amputation in 7. In 60% of cases in the limb salvage surgery group, we attempted wide resection with positive microscopic margin compared to only 16.7% in the amputation group. Local recurrence was higher in the limb salvage group. Overall survival was 18 months for mean follow up of 14.8 months. Median survival was 19 months in the limb salvage group compared to 9 months in amputation group. The outcome of surgical treatment of pelvic osteosarcoma remains poor despite advancements in musculoskeletal oncology treatment.

Item Type: Article (Journal)
Additional Information: 5770/29811
Uncontrolled Keywords: Pelvic osteosarcoma, limb salvage surgery, hemipelvectomy, margins, oncologic outcomes
Subjects: R Medicine > RB Pathology
R Medicine > RC Internal medicine > RC254 Neoplasms. Tumors. Oncology (including Cancer)
R Medicine > RD Surgery > RD701 Orthopedics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Department of Orthopaedics, Traumatology & Rehabilitation
Date Deposited: 18 Apr 2013 15:27
Last Modified: 16 Nov 2015 15:03
URI: http://irep.iium.edu.my/id/eprint/29811

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