Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital

Nagi, Abdul Ghaffar and Murad, Raffat and Baig, Mukhtiar (2011) Dengue fever outbreak among children in Karachi : experience at a tertiary care children hospital. The Journal of Bahria University Medical and Dental College, 1 (2). pp. 44-48. ISSN 2220-7562

PDF (Dengue fever outbreak among children in Karachi: experience at a tertiary care children hospital) - Published Version Restricted to Repository staff only Download (1MB) | Request a copy

Abstract

Objective: To study the natural history of disease in terms of clinical presentation and outcome in hospitalized children with confirmed dengue cases. Methods: A case series study was conducted at National Institute of Child Health (NICH), Karachi from September through November 2006. Children presented with fever and presence of at least 2 clinical manifestations of suspected dengue infection according to WHO criteria were included in study. Patients were followed regarding clinical presentation, investigations, management and outcome. Results: A total of 152 children admitted with suspicion of having dengue fever were evaluated in the study. Dengue fever antibody IgM tested on all suspected patients along with CBC, PT/aPTT, Blood C/S, Serum protein and chest X- ray. Dengue fever IgM was positive in 111 patients. A significant majority of dengue patients belonged to peri urban slums. Common presenting symptom among dengue patients was fever (100%), rash (71.17%), vomiting (52.25%), hemorrhagic manifestation (36.03%) and fits (5.40%). Among 111 dengue positive cases 65 (58.58%) were Dengue Fever (DF) cases, 40 (36.03%) were Dengue Hemorrhagic Fever (DHF) and 6 (5.4%) were cases of Dengue Shock Syndrome (DSS). Three patients expired during their stay in hospital. Conclusion: A high percentage of dengue positive cases among suspected patients and a significant proportion of dengue hemorrhagic fever and dengue shock syndrome cases demands careful investigation and management.

Item Type:	Article (Journal)
Additional Information:	6692/28688
Uncontrolled Keywords:	Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
Subjects:	R Medicine > RJ Pediatrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Paediatrics
Depositing User:	Assoc. Prof. Dr. Abdul Ghaffar Nagi
Date Deposited:	22 Jan 2013 09:26
Last Modified:	13 Feb 2013 17:24
URI:	http://irep.iium.edu.my/id/eprint/28688

Actions (login required)

View Item