Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia

Akter, Seikh Farid Uddin and Abdul Rani, Mohammed Fauzi and Ab Rahman, Jamalludin and Sulong, Sarina and Md Aris, Mohd Aznan and Phang, Ing Chia and Khattak, Muhammad Muzaffar Ali Khan and Bakhtiar, M. Taher (2012) Alleles of apolipoprotein E gene (APOE) as genetic determinants of dementia. In: Malaysian Science and technology Congress (MSTC 2012), 19 - 21 Nov 2012, SIME DARBY Convention Center, Bukit Kiara, Kuala Lumpur. (Unpublished)

PDF (Alleles of apolipoprotein E gene (APOE)) - Accepted Version Restricted to Registered users only Download (5MB) | Request a copy

Abstract

Dementia is emerging as a silent epidemic for rapidly developing countries like Malaysia. Its prevalence and a generic determinant assessment were the focused objectives of this study. There were two phases in this study - an initial descriptive phase followed by an analytic phase. Data were collected from 197 study subjects intially for the secriptive phase; 65 dementia cases and 103 age matched controls for analytic phase using a questionnaire for personal profile and other related factors. Furthermore, the standard protocols were followed to determine the frequencies of the alleles of apolipoprotein E gene (APOE). The statistical analyses were performed using the SPSS for Windows, Version 17. In addition to descriotive statistics such as percentage, pertinent inferential statistical analyses such as chi square test were performed. It appears from the inital descriptvie study that dementia was the leadinf disease (72.1%) of the identified diseases among study subjects.

Item Type:	Conference or Workshop Item (Full Paper)
Additional Information:	5187/27960
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Internal Medicine Kulliyyah of Pharmacy > Department of Pharmaceutical Technology Kulliyyah of Science > Department of Biotechnology
Depositing User:	Ms Rosyidah Taju Rahim
Date Deposited:	28 Dec 2012 13:27
Last Modified:	10 Mar 2016 14:56
URI:	http://irep.iium.edu.my/id/eprint/27960

Actions (login required)

View Item