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Predictors of in-hospital mortality in primary intracerebral haemorrhage in rural Malaysia

Rathor, Mohammad Yousuf and Abdul Rani, Mohammed Fauzi and Ab Rahman, Jamalludin and How, Soon Hin and Abdul Rashid, Mohd Amran and Che Abdullah, Shahrin Tarmizi and Omar, Ahmad Marzuki and Shah, Anis (2011) Predictors of in-hospital mortality in primary intracerebral haemorrhage in rural Malaysia. In: Asia Pacific Stroke Conference 2011, 29 Sep-1 Oct 2011, Colombo, Sri Lanka.

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Abstract

Introduction: Primary intracerebral hemorrhage (PICH) remains the deadliest and most disabling form of stroke. Despite that, there is paucity of epidemiological data on this condition in Malaysia. The aim of our study was to analyse the frequency of various risk factors among our PICH patients and determine the predictors of in-hospital mortality. Methods: A prospective study conducted among PICH patients at a tertiary care level hospital. Results: A total of 160 (93 male and 67 female) eligible patients with age range from 25 to 85 years (mean age 58.30 ± 11.44 years) were evaluated. Hypertension was the commonest risk factor (74.4%), followed by diabetes mellitus (18.8%) and cigarette smoking (36.3%). The commonest localization of ICH was lobar (43.8%) followed by basal ganglia / thalamus (28.1 %) and multilobar (13.1%). The overall mortality was 32.5 %. About one third (32.7%) of the deaths occurred within first 24 hours, this rose to 38.5% within first 2 days and 84.6% within one week. The significant independent predictors of acute in- hospital mortality were posterior fossa bleed (OR 11.01; 95% CI 3.21 to 37.81), hematoma volume >60ml (OR 4.72; 95% CI 1.34 to 16.64), mid line shift (OR 3.32; 95% CI 1.05 to 10.50) and intraventricular extension of haemorrhage (OR 5.69; 95% CI 2.24 to 14.47). Conclusion: PICH is associated with high mortality. The characteristics of hematoma and its localization was the most important factor to determine in-hospital mortality. Keywords: Primary intracerebral haemorrhage

Item Type: Conference or Workshop Item (Poster)
Additional Information: 2309/27571
Uncontrolled Keywords: Primary intracerebral haemorrhage, Clinical profile, Outcome, Glasgow coma scale, Malaysia
Subjects: R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011)
Kulliyyah of Medicine > Department of Internal Medicine
Kulliyyah of Medicine > Department of Radiology
Depositing User: Professor Dr Mohammad Yousuf Rathor
Date Deposited: 18 Dec 2012 10:34
Last Modified: 10 Mar 2016 15:01
URI: http://irep.iium.edu.my/id/eprint/27571

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