Investigation of antioxidant activity and phytochemical constituents of Artocarpus altilis

Kamal, Tara and Zuberdi, Ahmad Muzammil and Abdullateef, Raji Akintunde and Omar, Muhammad Nor (2012) Investigation of antioxidant activity and phytochemical constituents of Artocarpus altilis. Journal of Medicinal Plants Research, 6 (26). pp. 4354-4357. ISSN 1996-0875

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Abstract

The phytochemical screening study and the antioxidant activity test of the twigs of Artocarpus altilis has been done for the first time. The Artocarpus genus is known to produce a large number of secondary metabolites, and is specifically rich in phenylpropanoids such as flavonoids and flavones. Results of this study indicated that A. altilis (twigs) contain terpenoids, saponins, phenolic group, flavonoids, glycoside, steroids and tannins, while alkaloid test yielded negative result. Investigation on these chemical compounds was done using the standard technique for assay of phytochemical constituents, with modification. The dried plant was extracted by using soxhlet apparatus using three solvents namely hexane, dichloromethane (DCM) and methanol, and it was observed that the plant has a characteristic of antioxidant using DPPH assay. DCM extract of Artocarpus altilis has a remarkable antioxidant activity with an IC50 value of 0.015 mg/ml compared with the standard butylated hydroxytoluene (BHT). This finding supports the possibility of using this plant for medicinal treatments.

Item Type:	Article (Journal)
Additional Information:	5626/24994
Uncontrolled Keywords:	phytochemical, antioxidant, 1, 1-diphenyl-2-picrylhydrazyl (DPPH), Artocrapus, medical treatment
Subjects:	Q Science > QR Microbiology > QR180 Immunology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Biotechnology
Depositing User:	Prof Dr Muhammad Nor Omar
Date Deposited:	10 Aug 2012 12:24
Last Modified:	10 Aug 2012 12:24
URI:	http://irep.iium.edu.my/id/eprint/24994

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