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Bone formation at posterolateral intertransverse lumbar fusion

Buyong, Zunariah and Zakaria@Mohamad, Zamzuri and Khalid, Kamarul Ariffin and Zulkifly, Ahmad Hafiz and Ab Rahman, Jamalludin and Abdul Wahab, Amran and Abdel Wahab, Emad Mohamad Nafie and Fazan, Fazilah (2010) Bone formation at posterolateral intertransverse lumbar fusion. In: IIUM Research, Innovation & Invention Exhibition (IRIIE 2010), 26-27 January 2010, Kuala Lumpur.

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This study aimed to compare bone formation in posterolateral lumbar fusion after implantation with hydroxyapatite (HA) granules alone, HA granules mixed with autologous platelet rich plasma (HA-PRP) and autograft. Twenty-four New Zealand white rabbits were used. The rabbits were randomized into two groups of twelve rabbits each based on the graft materials used. All the rabbits underwent single level bilateral posterolateral intertransverse lumbar fusion between L5 and L6 segment of lumbar spines. One side of the animals was implanted with either HA alone or HA mixed with PRP. While the contra lateral side was implanted with autograft, and served as the control. The animals were sacrificed after six weeks post-implantation for undecalcified histological and radiological assessments. Results showed that the control group with autograft healed with a good fusion mass. Interestingly, HA granules only group healed with better bone formation than HA-PRP.

Item Type: Conference or Workshop Item (Poster)
Additional Information: 5178/23970
Uncontrolled Keywords: IRIIE 2010, bone formation in posterolateral lumbar
Subjects: R Medicine > R Medicine (General)
R Medicine > RD Surgery > RD701 Orthopedics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011)
Kulliyyah of Medicine > Department of Department of Orthopaedics, Traumatology & Rehabilitation
Depositing User: Assoc. Prof. Dr. Kamarul Ariffin Khalid
Date Deposited: 21 Jun 2012 13:07
Last Modified: 10 Mar 2016 15:02
URI: http://irep.iium.edu.my/id/eprint/23970

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