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Bio-pharmaceuticals : emerging proniosomes in drug delivery

Nanjwade, Basavraj K. and Singh, Jeet and Ahmad, Kausar and Manvi, F. V. (2011) Bio-pharmaceuticals : emerging proniosomes in drug delivery. In: Biodegradable polymers : processing, degradation and applications. Nova Science Publishers, Hauppauge, New York, pp. 639-654. ISBN 9781612095349

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Abstract

Vesicular drug delivery system like liposomes and niosomes, sometimes drugs are not delivered in a desired manner because of aggregation, sedimentation, stability problems and tedious method of production. By using ‘Proniosomes’ as carrier for drug delivery these problems of drug delivery can be reduced because they are easy to prepare and having good physical and chemical stability. Proniosomes also have been shown wide applicability in pharmaceutical and medical field; they are promising carrier for systemic and controlled delivery of drugs. Entrapment in the lipidic or core material of the proniosome can help in the delivery of drugs with poor solubility, lower permeability and first pass effect. Proniosome are also useful for the delivery of hydrophobic and amphiphilic drugs. In the present review various methods used in proniosome preparation are discussed. A brief focus on characterization parameters, factors affecting preparation and applications are presented.

Item Type: Book Chapter
Additional Information: 4551/13816
Uncontrolled Keywords: Proniosomes, Liposomes, Niosomes, Hydrophobic drugs, Amphiphilic drugs
Subjects: R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Depositing User: DR KAUSAR AHMAD
Date Deposited: 08 May 2013 13:55
Last Modified: 25 Jun 2013 19:08
URI: http://irep.iium.edu.my/id/eprint/13816

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