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Central nervous system tumour in pregnancy, a diagnostic challenge or management quandary

Abd Malik, Nur Rashidah and Ali Yeon, Amira Anis and Ismail, Hamizah and Mohd Rashid, Nurul Nafizah and Wahab, Mohd Ghaddafi and Awang, Mohamed Saufi (2026) Central nervous system tumour in pregnancy, a diagnostic challenge or management quandary. IUM Medical Journal Malaysia, 25 (2). pp. 172-176. ISSN 2735-2285

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Abstract

Central nervous system (CNS) tumour, being rare in pregnancy, posed different challenges. We report three challenging cases managed at our centre. The first case was a diagnostic puzzle, bringing a myriad of differentials since the eighth week of gestation. Diagnosis made after magnetic resonance imaging (MRI) post-delivery at 35 weeks of gestation led to cervical spine meningioma excision surgery and subsequent progressive, remarkable neurologic recovery. Two additional cases were not a diagnostic mystery, yet they posed management challenges. The second case was diagnosed with a cerebellar tumour complicated with hydrocephalus at a pre-viable gestation. Pregnancy was able to be prolonged up to viability at extreme prematurity at 26 weeks when she needed delivery with subsequent cerebellar haemangioma excision and recovery. However, the third case became pregnant during follow-up after radiation therapy for brain glioma, with persistent symptoms necessitating termination of pregnancy.

Item Type: Article (Case Report)
Uncontrolled Keywords: CNS tumour, central nervous system tumour, pregnancy
Subjects: R Medicine > RG Gynecology and obstetrics > RG500 Obstetrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Obstetric & Gynecology
Depositing User: Dr Nur Rashidah Abd Malik
Date Deposited: 13 Apr 2026 10:10
Last Modified: 13 Apr 2026 10:10
Queue Number: 2026-04-Q2787
URI: http://irep.iium.edu.my/id/eprint/128237

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