Nasreen, Hashima E and Syed Ahmad, Syarifah Amirah and Tyrrell, Marie and Mat Zin, Nora and Abd. Aziz, Karimah Hanim and Md. Aris, Mohd. Aznan and Nahar Kabir, Zarina (2026) Telephone-based intervention improves quality of life among family caregivers of persons with dementia in Malaysia: the mediating role of caregiver burden. BMC Geriatrics, 26 (1). pp. 1-12. E-ISSN 1471-2318
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Abstract
Background: Family caregiver (FC) of persons with dementia (PWD) are increasingly affected by mental and physical health which leads to poor quality of life (QoL). Telephone-based interventions offer flexible solution to support caregivers of PWD but the effectiveness needs further evaluation. This study aimed to assess the effectiveness of a telephone-based intervention in improving QoL among FC of PWD and to examine the role of caregiver burden as a mediating factor. Methods: A randomized control trial study was conducted involving 121 FCs, divided into intervention (n = 60) and control (n = 61) groups. The intervention group received a 10-week intervention by the healthcare professionals via telephone. QoL were measured using the validated Malay version of Control, Autonomy, Self-Realization and Pleasure (CASP-19) at baseline (T0) and endline (T1). Intention-to-treat (ITT) analysis was performed to determine the independent effect of the intervention on QoL, and mediation analysis was conducted using the multiple linear regression and bootstrap analysis. Results: Participants in the intervention group showed a statistically significant improvement in QoL (β = 5.00, 95% CI 2.21–7.78, p = 0.001). Mediation analysis revealed that caregiver burden mediated the relationship between the telephone-based intervention and QoL. Additionally, reduction of caregiver burden was observed to mediate the relationship between telephone-based intervention and reduced anxiety symptoms. Conclusion: Telephone-based intervention was effective in improving the QoL among FCs of PWD. The findings also suggest that caregiver burden plays a mediating role in this process, underscoring the need for policymakers to integrate burden-reduction training into future programs.
| Item Type: | Article (Journal) |
|---|---|
| Uncontrolled Keywords: | Telephone-based intervention, Quality of life, Family caregiver, Dementia, Mediation analysis |
| Subjects: | R Medicine > RZ Other systems of medicine > RZ400 Mental healing |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Medicine Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Psychiatry |
| Depositing User: | Dr. HASHIMA E NASREEN |
| Date Deposited: | 16 Mar 2026 09:48 |
| Last Modified: | 16 Mar 2026 09:48 |
| Queue Number: | 2026-03-Q2546 |
| URI: | http://irep.iium.edu.my/id/eprint/127915 |
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