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Primary plasma cell leukemia presented as progressive paraplegia: a case report

Hasmoni, Mohamed Hadzri and Abdul Wahid, Fadilah and Cheong, Soon Keng (2009) Primary plasma cell leukemia presented as progressive paraplegia: a case report. Southern Medical Journal, 102 (1). pp. 101-103. ISSN 0038-4348 (P), 1541-8243 (O)

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Abstract

Plasma cell leukemia (PCL) is a rare plasma cell disorder. It is the leukemic variant of multiple myeloma. A 52-year-old man with an atypical presentation of primary plasma cell leukemia is reported. The patient presented with paraparesis which progressively worsened to paraplegia. MRI of the spine showed an extradural mass causing cord compression and multiple bony erosions from soft tissue masses. Peripheral blood film examination and bone marrow aspiration showed numerous plasmablasts. Atypical cells expressed surface and cytoplasmic lambda light chain on immunochemical studies, surface CD45 and CD38. To our knowledge, primary PCL presenting with progressive paraplegia has not been reported in the literature.

Item Type: Article (Journal)
Additional Information: 4050/12330 Journal information Ranking: Medicine, General & Internal 90/151 Impact Factor: 0.759
Uncontrolled Keywords: cord compression, multiple myeloma, paraplegia, plasma cell leukemia
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Kulliyyahs/Centres/Divisions/Institutes: Kulliyyah of Medicine > Department of Internal Medicine
Depositing User: Dr Mohamed Hadzri Hasmoni
Date Deposited: 27 Dec 2011 16:33
Last Modified: 28 Dec 2011 07:06
URI: http://irep.iium.edu.my/id/eprint/12330

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