Che' Man, Mohamad and Adanan, Nur Azizah and Che Alhadi, Shahidah and Amiruddin, Salman (2025) Amlodipine-induced generalised exfoliative dermatitis: not to be missed! Asian Journal of Medicine and Health Sciences, 8 (1). pp. 288-294. E-ISSN 2637-0603
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Abstract
Amlodipine a calcium channel blocker (CCB), is commonly used in treating hypertension, coronary artery disease, and chronic kidney disease. It is considered a first-line treatment for high blood pressure. Amlodipine acts by selectively inhibiting voltage-gated L-type calcium ion channels, which consequently decreases systemic vascular resistance, total vascular resistance, and muscle contractility. We report a case of amlodipine-induced exfoliative dermatitis, highlighting the importance of recognizing this rare but serious cutaneous reaction to amlodipine, a commonly used drug in primary care. Prompt discontinuation of the offending drug and appropriate management are crucial for improving patient outcomes. Clinicians should maintain a high index of suspicion for drug-induced exfoliative dermatitis in patients presenting with generalized erythema and scaling after initiating new medications
| Item Type: | Article (Case Report) |
|---|---|
| Uncontrolled Keywords: | Amlodipine, calcium channel blocker, exfoliative dermatitis. |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology R Medicine > RM Therapeutics. Pharmacology > RM300 Drugs and their action |
| Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): | Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Surgery |
| Depositing User: | nur hakimah a manan |
| Date Deposited: | 22 Jul 2025 08:31 |
| Last Modified: | 22 Jul 2025 08:31 |
| URI: | http://irep.iium.edu.my/id/eprint/122158 |
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