A deceptive enemy: unmasking toxoplasma encephalitis IRIS in HIV hepatitis B coinfection individual with tuberculosis

Cheong, Xiong Khee and Zainulabid, Ummu Afeera and Kori, Najma and Periyasamy, Petrick (2025) A deceptive enemy: unmasking toxoplasma encephalitis IRIS in HIV hepatitis B coinfection individual with tuberculosis. In: 35th Congress of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Global), 11th - 15th April 2025, Messe Vien, Austria, Vienna.

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Abstract

Immune Reconstitution Inflammatory Syndrome (IRIS) is a paradoxical inflammatory response that is associated with HIV-infected individuals following initiation of antiretroviral therapy (ART), particularly in those with low CD4 and high viral load. The diagnosis of central nervous system (CNS) IRIS is challenging due to its varied manifestations and similarity to other opportunistic infections. Although Toxoplasma gondii encephalitis is a common HIV-related CNS infection, unmasking CNS-IRIS associated with toxoplasma infection is rarely reported. We described a young male with advanced HIV, hepatitis B, and disseminated tuberculosis who developed Toxoplasma encephalitis IRIS after ART initiation.

Item Type:	Proceeding Paper (Poster)
Uncontrolled Keywords:	Immune Reconstitution Inflammatory Syndrome (IRIS); antiretroviral therapy (ART); Toxoplasma gondii
Subjects:	R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Asst. Dr. Ummu Afeera Zainulabid
Date Deposited:	27 Oct 2025 21:40
Last Modified:	27 Oct 2025 21:40
URI:	http://irep.iium.edu.my/id/eprint/121933

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