Rapid nanopore sequencing as a key diagnostic tool in adrenal histoplasmosis after a year of uncertainty

Zainulabid, Ummu Afeera and Cheong, Xiong Khee and Kori, Najma and Periyasamy, Petrick and Abdul Muien, Muhammad Zahid and Musily, Raniza and Mohamed Rose, Isa and Zaidan, Noor and Ismail, Nordiana and Neoh, Hui-min and Han Min, Gan (2025) Rapid nanopore sequencing as a key diagnostic tool in adrenal histoplasmosis after a year of uncertainty. In: ESCMID Global 2025, 11 - 15 April 2025, Messe Wien, Vienna, Austria.

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Abstract

Histoplasmosis, caused by Histoplasma capsulatum, exhibits a broad clinical spectrum, ranging from asymptomatic pulmonary infections to disseminated disease. Atypical presentations, such as isolated adrenal involvement, can pose significant diagnostic challenges, underscoring the need for rapid and accurate diagnostic tools. This report highlights a challenging case of adrenal histoplasmosis diagnosed through ampli- con-based Nanopore sequencing after a year of diagnostic uncertainty.

Item Type:	Proceeding Paper (Poster)
Uncontrolled Keywords:	Nanopore sequencing; Histoplasma capsulatum; adrenal histoplasmosis
Subjects:	R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Asst. Dr. Ummu Afeera Zainulabid
Date Deposited:	04 Jul 2025 10:17
Last Modified:	04 Jul 2025 10:17
URI:	http://irep.iium.edu.my/id/eprint/121857

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