Focal segmental glomerulosclerosis – a report from primary care perspective

Ithnain, Khairunnisa and Shalihin, Mohd Shaiful Ehsan and Nik Yahya, Nik Hasimah (2025) Focal segmental glomerulosclerosis – a report from primary care perspective. Asian Journal of Medicine and Health Sciences, 8 (1). pp. 259-267. E-ISSN 2637 - 0603

PDF - Published Version Restricted to Repository staff only Download (299kB) | Request a copy

Abstract

Nephrotic syndrome is a prevalent condition characterized by heavy proteinuria, hypoalbuminemia, peripheral oedema, and hypercholesterolemia. It primarily affects the lower extremities and can arise from a variety of underlying causes. Focal segmental glomerulosclerosis (FSGS) is a leading cause of primary glomerular disease in adults, accounting for approximately 35% of cases and up to 80% in African American populations. Early diagnosis and appropriate management are essential to mitigate morbidity, mortality, and associated complications. We report the case of a young female presenting with bilateral lower limb swelling and symptoms of fluid overload, ultimately diagnosed with nephrotic syndrome. The diagnosis was confirmed through a simple urinalysis. Despite implementing dietary salt restriction and treatment with diuretic therapy, including daily administration of loop diuretics, the patient did not achieve a therapeutic response. Consequently, she required lifelong renal replacement therapy.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Focal segmental glomerulosclerosis, Primary care, Quality of life
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Family Medicine (Effective: 1st January 2011) Kulliyyah of Medicine
Depositing User:	Dr Mohd Shaiful Ehsan Shalihin
Date Deposited:	30 May 2025 10:36
Last Modified:	30 May 2025 10:36
URI:	http://irep.iium.edu.my/id/eprint/121268

Actions (login required)

View Item