Bacteremia due to the fastidious bacterium Granulicatella adiacens: a diagnosis that was almost missed

Ding, C. H. and Wahab, A. A. and Mohamed, Nurdiyana and Wong, P. F. (2025) Bacteremia due to the fastidious bacterium Granulicatella adiacens: a diagnosis that was almost missed. Tropical Biomedicine, 42 (1). pp. 58-60. E-ISSN 2521-9855

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Abstract

Bacteremia due to Granulicatella adiacens has been rarely reported in the medical literature. A middle-aged gentleman developed necrotizing fasciitis on his left second toe after stepping on a nail. A ray amputation was performed and ceftazidime-susceptible Pseudomonas aeruginosa was isolated from his bone culture. However, while receiving ceftazidime for the necrotizing fasciitis, his blood culture vial was positive for gram-positive cocci-shaped bacteria in short chains which grew as tiny non-lytic colonies on sheep blood agar only following extended incubation. There was no culture evidence of P. aeruginosa in the same blood specimen. The gram-positive organism was conclusively identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry as G. adiacens. The patient was treated with benzylpenicillin (to which the organism tested susceptible) for 14 days before he was discharged home. © 2025, Malaysian Society for Parasitology. All rights reserved.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Anti-Bacterial Agents; Bacteremia; Carnobacteriaceae; Fasciitis, Necrotizing; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Penicillin G; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; antiinfective agent; penicillin G; bacteremia; Carnobacteriaceae; case report; diagnosis; drug therapy; Gram positive infection; human; isolation and purification; male; matrix-assisted laser desorption-ionization mass spectrometry; microbiology; middle aged; necrotizing fasciitis
Subjects:	R Medicine > RB Pathology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User:	Fuziah Arifin
Date Deposited:	22 May 2025 12:01
Last Modified:	22 May 2025 12:01
URI:	http://irep.iium.edu.my/id/eprint/121150

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