A follow up study on lung cancer survival in the state hospital in east coast state of Pahang

Balakrishnan, Sivasubramaniam and Jamalludin, Ab Rahman and Koya kutty, Shaheedah and Abdul Razak, Megat Razeem and Ibrahim, Aishah and How, Soon Hin (2025) A follow up study on lung cancer survival in the state hospital in east coast state of Pahang. IIUM Medical Journal Malaysia, 24 (02). pp. 97-103. ISSN 1823-4631 E-ISSN 2735-2285

	PDF - Published Version Restricted to Registered users only Download (410kB) | Request a copy
	PDF - Published Version Restricted to Registered users only Download (200kB) | Request a copy

Abstract

INTRODUCTION: There is lack of data of lung cancer survival in Malaysia. MATERIAL AND METHODS:This study was to determine the survival of lung cancer patients andfactors affecting the survival in Kuantan, Pahang. A total of 170 lung cancer patientsconfirmed by histology from 1st January 2014 to 31 December 2017 were recruited inthe study. Their demographic data, ECOG performance status, staging and treatmentwere recorded. Survival time was defined in weeks from the date of histologicaldiagnosis made to the date of death of the patients. Kaplan-Meier curve was used todetermine the median overall survival and log-rank test was used to test the survivaldifferences between each subgroup. Multivariate analysis using COX regression wasused to determine factors affecting its survival.RESULTS: The median age of the170 patients was 63 years old, majority were males (74%) and smokers (64%).Adenocarcinoma (74.7%) was the most common histology followed by squamous cellcarcinoma (18.8%). Almost all patient presented at the clinic at stage 3 or 4 (98%) butmajority had ECOG 0-2 (64.3%). Median overall survival was 28.7 weeks. In themultivariate analysis, “supportive treatment” and “poor ECOG performance status”were independent predictors of death with thehazard ratio of 1.4 (95%CI 1.17 to 1.66)and 3.0 (95%CI 2.05 to 4.39) times respectively.CONCLUSION: Majority of lungcancer patients in Pahang presented with advanced disease with overall median survivalof 28.7 weeks. Patients treated with supportive care and poor ECOG performancestatus were the two independent poor prognostic factors for survival.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Lung cancer survival, HTAA, Pahang
Subjects:	R Medicine > RC Internal medicine > RC254 Neoplasms. Tumors. Oncology (including Cancer) > RC261 Cancer and other malignant neoplasms
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine
Depositing User:	Asst. Prof SIVASUBRAMANIAM BALAKRISHNAN
Date Deposited:	11 May 2025 13:21
Last Modified:	11 May 2025 13:21
URI:	http://irep.iium.edu.my/id/eprint/120506

Actions (login required)

View Item