Azadirachta Indica (Semambu) in traditional Malay medical manuscripts and assessment of bioactive compounds

Ramya, Razanah and Othman, Rashidi and Mohd Hatta, Farah Ayuni and Wan Sulaiman, Wan Syibrah Hanisah and Mohd Latiff, Nur Hanie (2024) Azadirachta Indica (Semambu) in traditional Malay medical manuscripts and assessment of bioactive compounds. Asian Journal of Environment, History and Heritage, 8 (1). pp. 21-32. ISSN 2590-4213 E-ISSN 2590-4310

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Abstract

Azadirachta indica (neem) is an Asia native plant from Meliaceae family, which has been recognized for its pharmaceutical potential for ages and contain numerous bioactive phytochemicals with therapeutic potential. This research aims to examine the ethnomedicinal plants that have been recorded in transliterated manuscripts and to discover the bioactive compounds. For methodology, secondary data were obtained from five selected Malay medical books. The experimental design involved two extraction methods, namely water extraction and sequential alkaline extraction. The data was qualitatively and quantitatively analyzed by Total Phenolic Content (TPC), and High-Performance Liquid Chromatography (HPLC). The findings from the Malay medical manuscript indicate that most diseases were physical illnesses. The total phenolic content of A. indica was 779.89 ± 12.32 µg GAE/g DW, and the phenolic acids detected by HPLC in both extractions were Vanillic acid, trans-p coumaric acid, and ferulic acid. In conclusion, this study demonstrates that A. indica has a huge potential for further exploration in pharmaceuticals.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Azadirachta indica, Malay medical manuscript, ethnomedicine, phenolic compound, antibacterial activities, ethnoscience.
Subjects:	Q Science > QK Botany S Agriculture > S Agriculture (General) S Agriculture > S Agriculture (General) > S494.5.S86 Sustainable agriculture S Agriculture > SB Plant culture S Agriculture > SD Forestry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	International Institute for Halal Research and Training (INHART) Kulliyyah of Architecture and Environmental Design Kulliyyah of Architecture and Environmental Design > Department of Landscape Architecture
Depositing User:	DR NUR HANIE MOHD LATIFF
Date Deposited:	25 Jul 2024 08:52
Last Modified:	25 Jul 2024 08:55
URI:	http://irep.iium.edu.my/id/eprint/113363

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