In vivo studies of Lepidium meyenii or maca in animal models of diabetes mellitus and other metabolic syndrome-related diseases- a scoping review

Othman, Najwa Hanim and Ismawi, Hidayatul Radziah and Mohd Zainudin, Maizura and Abd Fuaat, Azliana (2024) In vivo studies of Lepidium meyenii or maca in animal models of diabetes mellitus and other metabolic syndrome-related diseases- a scoping review. IIUM Medical Journal Malaysia, 23 (2). pp. 3-11. ISSN 1823-4631 E-ISSN 2735-2285

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Abstract

Lepidium meyenii or Maca is a Peruvian plant that belongs to the Brassicaceae family. Maca has various attributed health benefits due to the diversity of its bioactive compounds. Studies reveal that Maca is effective for many purposes including in the treatment of diabetes mellitus (DM) and other metabolic syndrome-related diseases. This review aims to uncover previously identified underlying anti-diabetic effects of Maca as well as its potential in the treatment of other conditions linked to metabolic syndrome in animal models in vivo. A scoping review of the literature was conducted using a protocol by Arksey and O’Malley. The protocol centred on the identification of research questions, identification and selection of relevant studies, data charting and collating, summarizing, and reporting the findings. Searches were conducted using Semantic Scholar, Scopus, PubMed Central, and ScienceDirect. Six studies were included in the review. The studies varied in terms of purpose, methodology, and detail of findings. They include the administration of Maca in different types of animal models and its effect on several biochemical parameters. There is fundamental scientific evidence from this review that supports the anti-diabetic properties of Maca in animal models of DM and other metabolic syndrome-related diseases. However, the scarcity of reports indicates the need for more rigorous studies in the future.

Item Type:	Article (Review)
Additional Information:	5472/111719
Uncontrolled Keywords:	Lepidium meyenii, diabetes, metabolic syndrome (MetS), animal
Subjects:	R Medicine > RC Internal medicine > RC627 Specialties of Internal Medicine-Metabolic Diseases R Medicine > RM Therapeutics. Pharmacology
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User:	Dr Hidayatul Radziah Ismawi
Date Deposited:	03 Apr 2024 15:38
Last Modified:	04 Apr 2024 08:21
URI:	http://irep.iium.edu.my/id/eprint/111719

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