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Prehypertensive state, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia

Abdullah, Aszrin and Mohd Shah, Azarisman Shah and Ab Rahman, Jamalludin and Mohd Noor, Noriah and Abdul Razak, Tariq (2015) Prehypertensive state, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia. International Medical Journal Malaysia, 14 (Suppl. 1). pp. 9-10. ISSN 1823-4631 E-ISSN 2735-2285

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Introduction: Hypertension is an important risk factor for Cardiovascular Disease in Malaysia. Hypertension prevalence is at 42.6% and population-based control is poor at 26.8%. Objective: The objective of the study is to ascertain the cardiovascular risk profile of prehypertensive and mildly hypertensive young adults against age-matched controls in rural Malaysia. Methodology: 484 subjects attending primary care clinics were screened, 91 young adults with pre/mild hypertension and normotensive, age-matched controls were enrolled. The blood pressure and biochemical profiles for both groups were assessed and compared. Results: Fifty-four subjects and 37 controls were enrolled. Amongst subjects, 46.3% had prehypertension and 53.7% had mild hypertension. Mean values compared to age-matched controls for MAP were 102.68 - 7.48 vs 83.25 - 6.08 mmHg (p<0.001), LDL 3.75 t 0.95 vs 3.32+ 0.93 mmol/L (p-0.03), FBS 4.65 t 0.54 vs 4.33 t 0.42 mmol/L (p=0.03), BMI 28.81 + 5.16 vs 24.12 + 4.91 (p< 0.001). The mean BP was significantly associated with BMI, FBS, triglycerides HDL and the TC/HDL ratio Conclusions: Greater BMI, FBG, HDL, triglyceride levels and TC/HDL ratio characterised the young adults with pre/mild hypertension. The data suggests that hypertension in young adults is secondary to metabolic syndrome.

Item Type: Article (other)
Uncontrolled Keywords: Hypertension, young adults, Prehypertensive state, metabolic syndrome, cardiovascular risk factors
Subjects: Q Science > QP Physiology
R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Basic Medical
Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011)
Kulliyyah of Medicine > Department of Internal Medicine
Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Basic Medical Sciences
Depositing User: DR Aszrin Abdullah
Date Deposited: 27 Feb 2024 15:46
Last Modified: 27 Feb 2024 16:14
URI: http://irep.iium.edu.my/id/eprint/110988

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