Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis

Abdullah, Aszrin and Mohd Shah, Azarisman Shah and Mohd Noor, Noriah and Abdul Razak, Tariq (2015) Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis. International Medical Journal Malaysia, 14 (Suppliment Issue). pp. 8-9. ISSN 1823-4631 E-ISSN 2735-2285

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Abstract

Hypertension or high blood pressure (BP) is a condition that has a significant impact on the world's population morbidity and mortality. The World Health Report 2002, stated that high blood pressure caused 7.1 million deaths throughout the world, which was approximately 13% of total deaths worldwide. The body's arterial blood pressure control depends on short-term and long-term mechanisms. Short-term BP regulation is mediated by the autonomic nervous system (ANS) targeting the heart, vessels, and adrenal medulla. The sympathetic nervous systems (SNS) crucial involvement in stressful conditions and short term regulation of blood pressure is also widely accepted. There has also been increasing evidence and recognition of sympathetic augmentation as the main cause for essential hypertension in a significant number of patients especially those with no known attributable secondary causes and those who are young. We discuss the role of the adrenaline hypothesis in the pathophysiology of hypertension.

Item Type:	Article (other)
Uncontrolled Keywords:	Hypertension, blood pressure, sympathetic, adrenaline hypothesis
Subjects:	Q Science > QP Physiology R Medicine > R Medicine (General) R Medicine > RC Internal medicine
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine > Department of Internal Medicine Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Basic Medical Sciences
Depositing User:	DR Aszrin Abdullah
Date Deposited:	23 Feb 2024 11:45
Last Modified:	23 Feb 2024 11:45
URI:	http://irep.iium.edu.my/id/eprint/110983

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