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A systematic review on multiple purpose solution of contact lens Ingredients: benefits and risks

Mohd Hasali, Nor Hazwani and Ibrahim, Maizatul Akma and Zakaria, Nor Hafizah and Abdul Majid, Fadzilah Adibah and Hashim, Fatimah and Tuan Johari, Syed Tajudin (2023) A systematic review on multiple purpose solution of contact lens Ingredients: benefits and risks. IIUM Medical Journal Malaysia (IMJM), 23 (1). pp. 12-18. ISSN 1823-4631 E-ISSN 2735-2285

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Since the past decades, the prevalence of microbial keratitis (MK) has risen notably among contact lens (CL) wearers. The main contributor to this infection is the use of an inefficient CL disinfecting solution. This paper highlights a systematic review of articles from journals on the multipurpose solution (MPS) of CL ingredients available currently in the market. This review emphasizes the compositions of MPS to evaluate their effectiveness and risks to lens wearers. A search for original articles published was conducted through Scopus, PubMed, and Google Scholar databases, focusing on the keywords contact lens ingredients and preservatives, MPS, polyquaternium, biguanides, and MK. A thorough review was conducted to extract the data on the subjects from the generated searches. The review revealed that hydrogen peroxide (H2O2), polyhexamethylene biguanide (PHMB), povidone-iodine (P-I), and polyquaternium-1 (PQ-1) are the preferred MPS formulations in the current industry of CLs. These chemical ingredients are effective against causative agents of keratitis for faster disinfection and lower risks of microbial infections in CL users. Thus, proper hygienic practices must follow the guidance from the respective product manufacturers to prevent harmful risks of ocular diseases.

Item Type: Article (Review)
Uncontrolled Keywords: Acanthamoeba keratitis, microbial keratitis, contact lens, multi-purpose solution.
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RE Ophthalmology
R Medicine > RE Ophthalmology > RE88 Ophthalmic nursing (Including eye, ear, nose and throat combined)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RM Therapeutics. Pharmacology > RM695 Physical medicine. Physical therapy
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Science > Department of Plant Science
Depositing User: Dr Maizatul Ibrahim
Date Deposited: 18 Jan 2024 14:33
Last Modified: 18 Jan 2024 15:10
URI: http://irep.iium.edu.my/id/eprint/110236

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