The effects of intermittent fasting on cardiovascular health of prediabetes and type 2 diabetes mellitus patients: a systematic review

Afdzal Rasif, Muhamad Naif Hafizin and Nazri, Amirah Farhana and Soe, May Khin (2023) The effects of intermittent fasting on cardiovascular health of prediabetes and type 2 diabetes mellitus patients: a systematic review. In: IDF Virtual Congress 2023, 04-07 Dec 2023, Brussels, Belgium. (Unpublished)

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Abstract

Introduction: Type 2 diabetes mellitus and prediabetes are showing an increasing number of cases and are predicted to keep increasing over the years. Both conditions have a 2-3-fold increased risk of developing cardiovascular diseases. Intermittent fasting is one of the forms of dietary intervention being practiced in preventing and managing these conditions and their associated complications. There are many reported benefits of intermittent fasting for health, but no specific studies discussed regarding the effect of this practice on the cardiovascular health of these patients. Thus, this study aims to systematically review the benefits of intermittent fasting on the cardiovascular health of these groups of patients. Methodology: This systematic review followed the guidelines of PRISMA and was registered at PROSPERO with the registration number of CRD42022378349. A systematic literature search was conducted in PubMed, Scopus, Cochrane Library, Google Scholar and by using snowball technique. The articles retrieved were independently screened by two authors against the eligibility criteria in stages of title, abstract and full text. The risk of bias in the included studies were assessed independently by two authors using the Joanna Briggs Institute critical appraisal checklist. Data from all the included articles were extracted using a predetermined template. Result: Twelve studies were included in this study. Six studies recorded a low risk of bias while the other six studies had a moderate risk of bias. 3 studies recorded significant reduction for both systolic and diastolic blood pressure, and 3 studies showed significant improvement in the lipid profiles at the end of intervention. Conclusion: Intermittent fasting is beneficial for cardiovascular health of prediabetes and type 2 diabetes mellitus patients mainly by improving both systolic and diastolic blood pressure and the lipid profiles. Randomized controlled trials that investigate specifically the benefits of this practice on the cardiovascular health of these populations are needed to confirm the findings.

Item Type:	Proceeding Paper (Poster)
Additional Information:	4550/109755 This final year student research project is guided and supported financially by supervisor so that student was successfully able to present the e-poster at International conference, IDF virtual conference 2023.
Uncontrolled Keywords:	Intermittent Fasting, Cardiovascular health, Prediabetes, Type 2 Diabetes Mellitus type, Systematic review
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Pharmacy Kulliyyah of Pharmacy > Department of Basic Medical Sciences
Depositing User:	Dr May Khin Soe
Date Deposited:	02 Jan 2024 10:34
Last Modified:	04 Jan 2024 09:35
URI:	http://irep.iium.edu.my/id/eprint/109755

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