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Orally disintegrating film: a review of its formulation and manufacturing method

Liew, Kai Bin and Gobal, Ganesan and Mohd Rofiq, Hanifah and Phang, Hiu Ching and Lee, Siew-Keah and Ming, Long Chiau and Helal Uddin, A.B.M. and Chew, Yik Ling and Lakshminarayanan, Vijayakumar (2023) Orally disintegrating film: a review of its formulation and manufacturing method. Malaysian Journal of Medicine and Health Sciences, 19 (6). pp. 297-303. ISSN 1675-8544 E-ISSN 2636-9346

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Abstract

Oral route drug delivery system is still considered as the most convenient and patient friendly drug delivery route. Over the decades, many research has been performed to improve the functionality oral dosage form. Orally disintegrating film (ODF) is a newer oral drug delivery system, which is in the form of a thin film that will disintegrate in the oral cavity within a matter of seconds. The aim of this review paper is to recap ODF, its benefits, formulation contents and manufacturing method. With more research and development work has been conducted on ODF, the dosage form is expected to be manufactured and scaled up to be commercializable products to be sold in the market.

Item Type: Article (Review)
Additional Information: 4478/108956
Uncontrolled Keywords: orally disintegrating film, solvent casting, hot melt extrusion, compliance, polymer
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology
R Medicine > RS Pharmacy and materia medica > RS403 Materia Medica-Pharmaceutical Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy
Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Depositing User: Dr. A. B. M. Helal Uddin
Date Deposited: 18 Dec 2023 12:56
Last Modified: 18 Dec 2023 12:56
URI: http://irep.iium.edu.my/id/eprint/108956

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