The association of anthropometric characteristics, hormonal alterations and ovarian volume with polycystic ovarian syndrome

Mohammed Faridz, Sumayyah and Nusee, Zalina and Mohd Tohit, Nor Faiza and Ismail, Hamizah and Abu Ishak, Nurkhairulnisa and Abdul Rahim, Roslina and Abdullah, Nor Zamzila (2023) The association of anthropometric characteristics, hormonal alterations and ovarian volume with polycystic ovarian syndrome. In: Transforming Medical Healthcare Through Research. IIUM Press, Kuala Lumpur, Malaysia, pp. 109-121.

PDF (Book Chapter) - Published Version Restricted to Registered users only Download (6MB) | Request a copy

Abstract

Polycystic ovarian syndrome (PCOS) is one of the most frequent endocrinopathies affecting reproductive-aged women with varied prevalence in different countries, ranging between 6% to 34%. The exact aetiology of PCOS has not been fully understood. PCOS is associated with undesirable comorbidities, such as metabolic syndrome and insulin resistance. (Lee et al., 2009; Boyle et al., 2012; Ishak et al., 2012; Ding et al., 2018; Ganie et al., 2020) Many types of amino acid peptides or enzymes at molecular levels have been investigated over the years to find their correlation to PCOS in search of better diagnostic markers and treatment purposes. Unfortunately, the desired outcome has yet to be achieved. Among the hormones that have been studied include ghrelin, leptin, insulin, and glucose. The relationship between ovarian volume and other hormonal and metabolic factors were also explored, with some discovering a significant link. In the United States, about 4 million women were affected by PCOS and it costs up to $4.36 billion per annum for healthcare expenditure (Azziz et al., 2005). This is proof that the condition leads to a heavy economic burden. The results from previous studies on the association between hormones in PCOS women were varying and inconsistent. Furthermore, the study on this topic still lacks Asian data, including Malaysia.

Item Type:	Book Chapter
Uncontrolled Keywords:	PCOS women, Ghrelin, Leptin, Ovarian volume
Subjects:	Q Science > QP Physiology R Medicine > RC Internal medicine R Medicine > RC Internal medicine > RC803 Specialties of Internal Medicine-Diseases of The Digestive System. Gastroenterology R Medicine > RG Gynecology and obstetrics R Medicine > RG Gynecology and obstetrics > RG500 Obstetrics
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Basic Medical Kulliyyah of Medicine > Department of Community Medicine (Effective: 1st January 2011) Kulliyyah of Medicine > Department of Obstetric & Gynecology Kulliyyah of Medicine > Department of Pathology & Lab Medicine
Depositing User:	Dr ROSLINA ABDUL RAHIM
Date Deposited:	08 Dec 2023 10:57
Last Modified:	14 Jan 2024 14:24
URI:	http://irep.iium.edu.my/id/eprint/108645

Actions (login required)

View Item