Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters

Jamen, Shahrulnizam and Mohd Aris, Mohd Shukri and Shamsul Harumain, Zakuan Azizi and Zahaba, Maryam and Danial, Wan Hazman and Abdul Hadi, Hazrin (2023) Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters. Journal of Health and Translational Medicine (Special Issue 2). pp. 353-357. ISSN 1823-7339 E-ISSN 2289-392X

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Abstract

Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potential carcinogen for humans, meaning they may cause cancer and pose serious health complications, particularly for manufacturing workers. This highlights the need for better evaluation to determine worker exposure. In this study, suspended TiO2 nanoparticles were sampled using a nanoparticle respiratory deposition (NRD) sampler fitted with specially designed membrane filters and analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The digestion method used for titanium element recovery after nanoparticle sampling is crucial for optimal ICP-MS analysis. Therefore, this study aimed to investigate the most suitable digestion method. A microwave-acid digestion method using concentrated nitric acid and concentrated hydrochloric acid at a 7:4 ratio, with a run time of 30 minutes and the temperature set to 200°C showed remarkable titanium recovery compared to other methods. These findings may pave the way for optimal analysis of suspended TiO2 nanoparticles in assessing occupational exposure while promoting sustainability and eco-friendliness in resource utilization.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Nanoparticles, Occupational Health, ICP-MS, Workplace, Titanium Dioxide
Subjects:	Q Science > Q Science (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science Kulliyyah of Science > Department of Biotechnology Kulliyyah of Science > Department of Chemistry
Depositing User:	Dr Zakuan Azizi Shamsul Harumain
Date Deposited:	16 Oct 2023 09:00
Last Modified:	11 Mar 2024 10:45
URI:	http://irep.iium.edu.my/id/eprint/107178

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