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Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Towns, Clodagh and Richer, Madeleine and Jasaityte, Simona and Mohamed, Wael Mohamed Yousef and Stafford, Eleanor J. and Joubert, Julie and Antar, Tarek and Martinez-Carrasco, Alejandro and Makarious, Mary B. and Casey, Bradford and Vitale, Dan and Levine, Kristin and Leonard, Hampton and Pantazis, Caroline B. and Screven, Laurel A. and Hernandez, Dena G. and Wegel, Claire E. and Solle, Justin and Nalls, Mike A. and Blauwendraat, Cornelis and Singleton, Andrew B. and Tan, Manuela M. X. and Iwaki, Hirotaka and Morris, Huw R. (2023) Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2). npj Parkinson's Disease, 9. pp. 1-6. E-ISSN 2373-8057

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Abstract

The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia.

Item Type: Article (Journal)
Subjects: R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Medicine
Kulliyyah of Medicine > Department of Basic Medical
Depositing User: Dr Wael Mohamed
Date Deposited: 21 Sep 2023 15:18
Last Modified: 21 Sep 2023 16:00
URI: http://irep.iium.edu.my/id/eprint/106871

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