Unmasking a hidden culprit: a case of 'diphtheritic' colitis

Zainulabid, Ummu Afeera and Jaafar, Khairul Azhar and Che Aun, Azlida and Periyasamy, Petrick (2023) Unmasking a hidden culprit: a case of 'diphtheritic' colitis. In: APCCMI 2023 The 19th Asia Pacific Congress of Clinical Microbiology and Infection & The 26th Conference of the Korean Society of Clinical Microbiology, 6-8 Jul 2023, Seoul, Korea. (Unpublished)

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Abstract

Pseudomembranous colitis, originally referred to as "diphtheritic colitis" by Finney in the late 1800s, has transformed from a fatal postoperative complication to a prevalent complication of antibiotic use that can lead to severe morbidity. This case report presents a complicated situation of a 71-year-old female patient diagnosed with colorectal carcinoma who developed pseudomembranous colitis after undergoing multiple rounds of antibiotics and chemotherapy. Despite treatment for acute infectious gastroenteritis, she exhibited no improvement. She was later diagnosed with pseudomembranous colitis after a colonoscopy revealing yellow raised lesions on edematous and erythematous mucosa. The patient was successfully treated with a 10-day oral vancomycin course without further relapse. Risk factors for pseudomembranous colitis include previous antibiotic use, treatment with proton pump inhibitors, nonsteroidal anti-inflammatory drugs, corticosteroids, and chemotherapy. Management of nosocomial diarrhea requires various diagnostic tests to determine the best course of action as Clostridium difficile infection, a common cause of pseudomembranous colitis, can cause a range of symptoms.

Item Type:	Conference or Workshop Item (Poster)
Additional Information:	7459/106101
Uncontrolled Keywords:	diphtheritic colitis, pseudomembranous colitis, Clostridium difficile
Subjects:	R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Internal Medicine
Depositing User:	Asst. Dr. Ummu Afeera Zainulabid
Date Deposited:	27 Sep 2023 15:02
Last Modified:	04 Oct 2023 11:27
URI:	http://irep.iium.edu.my/id/eprint/106101

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