Five years melioidosis registry data from 2011 to 2015 in Pahang, Malaysia: a retrospective study

How, Soon Hin and Zainulabid, Ummu Afeera and Mohd Ibrahim, Mohamad Shafiq and Mahmud, Fatihah and Lim, Bee Chiu and Bhajan Singh, Kiren Kaur and Loh, Tian Chee and Ken, Voon Fong and Sulong, Mohd Rahim (2023) Five years melioidosis registry data from 2011 to 2015 in Pahang, Malaysia: a retrospective study. Bangladesh Journal of Infectious Diseases, 9 (1). pp. 7-14. ISSN 2411-4820 E-ISSN 2411-670X

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Abstract

Background: Melioidosis cases were conducted throughout the state of Pahang, Malaysia, from 2000 to 2004, and found that there were high annual incidences and mortality rates among melioidosis patients. A series of programs on medical education has since been introduced throughout Pahang, and a registry has been created to track the effects. Objective: We established and investigated the melioidosis registry with the aim of improving the state's melioidosis management Methodology: This comprehensive review of the 239 confirmed melioidosis cases from 1st January 2011 to 31st December 2015 was performed to trace the cultures from all microbiology laboratories in Pahang. Comparisons were made between these cases and previous records retrieved from the registry. Information was verified from the patient’s case note when necessary. Results: The patients, aged from 1 to 84 years, were predominantly males (78.2%), Malays (82.0%), and had a median age of 51 years. The most common predisposing factor present in 165 (69.0%) patients was diabetes, while the most common clinical presentation observed in 109(45.6%) patients was pneumonia. With outcomes that were known within 209 patients, 106(50.7%) of them did not survive, and while the other 103(51.6%) were fully discharged. Patients who were fully discharged received appropriate antibiotics for both intensive and eradication therapies. Twenty patients (8.4%) had culture-confirmed relapses. Conclusion: Despite improvements in patient management, especially in treatment involving antibiotics, mortality rates remained high. Collectively, these research have found important relationships and insights that contribute for further management of the illness at the state level.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Melioidosis; Burkholderia pseudomallei; registry; mortality; awareness; Malaysia
Subjects:	R Medicine > RC Internal medicine > RC111 Infectious and Parasitic Diseases
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine Kulliyyah of Medicine > Department of Internal Medicine Kulliyyah of Dentistry
Depositing User:	Asst. Dr. Ummu Afeera Zainulabid
Date Deposited:	07 Aug 2023 12:02
Last Modified:	07 Aug 2023 12:02
URI:	http://irep.iium.edu.my/id/eprint/105848

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