Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19

Tzar, Mohd Nizam and Meor Jamaludin, Wan Husna Barakah and Abdul Wahab, Asrul and Chuan, Hun Ding (2022) Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19. IDCases, 27. pp. 1-3. E-ISSN 2214-2509

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Abstract

The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co- infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed.

Item Type:	Article (Case Report)
Uncontrolled Keywords:	Dematiaceous Mycosis Coronavirus COVID-19 Antifungal Malaysia
Subjects:	R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Medicine
Depositing User:	Dr. Wan Husna Barakah Meor Jamaludin
Date Deposited:	04 Aug 2023 10:30
Last Modified:	04 Aug 2023 10:30
URI:	http://irep.iium.edu.my/id/eprint/105824

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