Role of herbal tea (camellia sinensis L. Kuntze, Zingiber officinale Roscoe and Morinda citrifolia L.) in lowering cholesterol level: a review and bibliometric analysis

Fadhlina, Anis and Alias, Nur Fatin Afifa and Sheikh Mohamed, Hassan Ibrahim and Zakaria, Nor Hafizah and Abdul Majid, Fadzilah Adibah and Hairani, Muhammad Afnan Shakir and Hudiyanti, Dwi (2023) Role of herbal tea (camellia sinensis L. Kuntze, Zingiber officinale Roscoe and Morinda citrifolia L.) in lowering cholesterol level: a review and bibliometric analysis. Journal of Agriculture and Food Research, 13. pp. 1-11. E-ISSN 2666-1543

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Abstract

Dyslipidemia is defined as an imbalance level of lipids in the blood which is manifested by hypercholesterolemia and requires effective treatments or preventions. Numerous studies have discussed the various medicinal properties of Camellia sinensis, Zingiber officinale, and Morinda citrifolia, however, no bibliometric study about the trends and use of these three plants in cholesterol management around the world. Hence, this study employed the Scopus database to review the available literature on the potential cholesterol-lowering effects of these medicinal plants. In total, 822 articles were extracted, covering 360 keywords. Bibliometric analysis was done using VOSviewer software to analyse the global trends of the published articles focusing on the keywords, authors, countries, publication sources, and documents. The bioactive compounds, mechanisms of action, drug-herb interaction, and safe dosage were also addressed. The three plants were used globally in Asia, Africa, Europe, North America and South America. Z. officinale was the most researched plant, while India produced the highest number of documents. It was observed that these plants were scientifically proven in lowering the low-density lipoproteins cholesterol, triglycerides, and total cholesterol while increasing the high-density lipoproteins cholesterol due to their powerful bioactive constituents such as theaflavin, flavonol, gingerol, paradol, and niacin. Their major bioactive compounds have various mechanisms of action in altering lipid levels which require further studies to explore their mechanisms and benefits in a polyherbal form. Certain herbal-drug interactions and dosage should be taken into consideration to ensure the safe and effective usage of these plants. Our results hold significance for traditional and empirical medical evidence of this topic. More research collaborations are also needed to uncover research gaps such as molecular mechanisms, polyherbal formulations, and clinical trials. This will help in recognizing herbal medicine as a treatment approach for dyslipidemia.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Bibliometric; Cholesterol; Dyslipidemia; Herbal tea; Lipid
Subjects:	Q Science > Q Science (General) Q Science > QK Botany R Medicine > R Medicine (General)
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Dentistry Kulliyyah of Dentistry > Department of Fundamental Dental and Medical Sciences
Depositing User:	Dr. Anis Fadhlina
Date Deposited:	10 Jun 2023 13:04
Last Modified:	24 Nov 2023 15:07
URI:	http://irep.iium.edu.my/id/eprint/104878

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