Anacardium occidentale Linn. Leaves and its medicinal properties

Nur Farahin, Puteri and Haron, Normah and Darnis, Deny Susanti and Md Zin, Noor Hasniza (2022) Anacardium occidentale Linn. Leaves and its medicinal properties. Malaysian Journal of Biochemistry & Molecular Biology, 25 (3). pp. 27-36. ISSN 1511-2616 E-ISSN 2600-9005

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Abstract

nacardium occidentale leaves, known as cashew leaves or Pucuk Gajus in Malay, is a member of the Anacardiaceae family that is widely grown in tropical countries such as Malaysia, India and Brazil. It had been traditionally used for treating many health problems as it contained many beneficial phytochemical compositions such as polyphenols, flavonoids, tannin, vitamin C and carotenoids. Its extract possesses antidiabetic activity, which prevents a sudden rise in postprandial blood glucose level by inhibiting α-amylase to slow down the breakdown of long-chain carbohydrates to glucose. It also controls the blood glucose level by inhibiting dipeptidyl peptidase IV (DPPIV), which prevents the rapid degradation of incretin and thus stimulates insulin secretion. Besides, it acts as an antioxidant agent to protect against lipid peroxidation and scavenge radicals. It showed antimicrobial properties by inhibiting the growth of pathogenic bacteria including Gram-positive Staphylococcus aureus and Bacillus subtilis, and Gram-negative Escherichia coli and Klebsiella pneumonia, and fungi which are Aspergillus niger, Penicillium digitatum and Colletotrichum gloeosporiodes. Furthermore, it exhibited antiulcerogenic effect by preventing gastric lesions and anti- inflammatory properties which interrupt the inflammation process by controlling cytokines secretion in macrophage lipopolysaccharide-stimulated cells. Therefore, A. occidentale may potentially be contributed to the treatment of various diseases, but continuous study is needed to determine further the bioactive compounds that are responsible for the mechanism of action.

Item Type:	Article (Journal)
Uncontrolled Keywords:	Anacardium occidentale; Cashew leaves; Antidiabetic; Medicinal properties
Subjects:	Q Science > Q Science (General) R Medicine > RM Therapeutics. Pharmacology R Medicine > RM Therapeutics. Pharmacology > RM147 Administration of Drugs and Other Therapeutic Agents
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button):	Kulliyyah of Science > Department of Biotechnology Kulliyyah of Science
Depositing User:	Dr. Normah Haron
Date Deposited:	02 Feb 2023 14:34
Last Modified:	02 Feb 2023 14:35
URI:	http://irep.iium.edu.my/id/eprint/103553

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