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A review on the development of granulation technology in the past two decades

Chew, Yik Ling and Kahlous, Yahia and Uddin, A.B.M. Helal and Sarker, Zaidul Islam and Liew, Kai Bin (2022) A review on the development of granulation technology in the past two decades. Journal of Pharmaceutical Negative Results, 13 (7). pp. 93-95. ISSN 0976-9234 E-ISSN 2229-7723

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Granulation is a technique that convert fine powder particles to granules which form appropriate agglomerate. It’s main function is to improve the powders flow and compressibility properties as well as to prevent segregation of the blend components. Traditionally, there are three types of granulation methods namely dry granulation, wet granulation and direct compressing. But, each one of these traditional methods has different disadvantage which prompted the researchers to modify and find new technique to granulate the powder. Among the new granulation technique are steam granulation, melt granulation, moisture activated dry granulation, foam granulation, pneumatic dry granulation technology and thermal adhesion granulation. Choosing a technique depends on the knowledge of advantages and disadvantages of each technique and how appropriate it is to the characteristics of each ingredient. This review mainly focusses on new techniques in granulation technologies for granules production.

Item Type: Article (Review)
Subjects: Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS192 Materia Medica-Pharmaceutical Technology
R Medicine > RS Pharmacy and materia medica > RS403 Materia Medica-Pharmaceutical Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Kulliyyah of Pharmacy
Depositing User: Dr. A. B. M. Helal Uddin
Date Deposited: 30 Dec 2022 09:31
Last Modified: 30 Dec 2022 09:31
URI: http://irep.iium.edu.my/id/eprint/102354

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