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Experimental design of supercritical fluid extraction: a review

Sharif, K. M. and Rahman, Md. Mokhlesur and Azmir, Jannatul and Awang, Mohamed and Akanda, Mohammed Jahurul Haque and Ferdosh, Sahena and Sarker, Md. Zaidul Islam (2014) Experimental design of supercritical fluid extraction: a review. Journal of Food Engineering, 124. pp. 105-116. ISSN 0260-8774

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Supercritical fluid extraction (SFE), a sustainable green technology leads a wide range of applications since the past decade. Like many other processes, SFE is sometimes criticized for its large number of factors which need to be properly adjusted before every single run. Experimental design and proper statistical analysis with small number of trials in adjusting the SFE parameters become popular in this regard. This paper is aimed to review the common experimental designs that are frequently used in the SFE process. Utilizations of different experimental designs in SFE with the intention of either screening the most influential factors or optimizing the selected factors are briefly reviewed. Strategies and recommendation addressing the choice of appropriate design, constructing design matrix, experimental trial and data analysis are discussed in this paper. For more application oriented readers of SFE, an effective and easy chart on choosing proper experimental design and a list of experimental design software are also included.

Item Type: Article (Journal)
Additional Information: 5269/32473 Corresponding author: Dr. Md. Zaidul Islam Sarker
Uncontrolled Keywords: Supercritical fluid extraction Experimental design Screening design Optimization design
Subjects: Q Science > QD Chemistry
Kulliyyahs/Centres/Divisions/Institutes (Can select more than one option. Press CONTROL button): Kulliyyah of Pharmacy > Department of Pharmaceutical Chemistry
Kulliyyah of Pharmacy > Department of Pharmaceutical Technology
Kulliyyah of Science > Department of Plant Science
Depositing User: Dr Mohd Mokhlesur Rahman
Date Deposited: 31 Oct 2013 11:20
Last Modified: 06 Sep 2017 09:57
URI: http://irep.iium.edu.my/id/eprint/32473

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